Tunicamycin (home):


3: Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 1996;28(6):697-699  

The Effect of Tunicamycin on the Interaction of Fibronectin and HT1080 Cells.

Cao LH, Zha XL.

Department of Biochemistry, Shanghai Medical University, Shanghai 200032, China.

We have found that the binding affinity of human plasma Fn to HT1O80 cell treated with TM was 2.61x1O(-8) M, the number of binding sites was 4.24x1O(4)/cell, while those of the control group was 2.50x1O(-8) M and 2.13x1O(5)/cell respectively. These results indicate that, the Fn binding sites on the cell surface decreased by 80% after TM treatment. The binding affinity of FnR in the TM-treated cell did not alter.

PMID: 12232600





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